The incidence of macroglossia has been reported as 11-60% in persons with Down Syndrome although the presence of true macroglossia has been questioned by some investigators. There is agreement, however, on the presence of a relative macroglossia due to the small palatal space and hypotonic tongue. Continue reading
Most common infection, most are transient with few untoward sequelae.
Some are life threatening (e.g., Meningoccus, Diphtheria)
Severe, recurrent, disseminated or persistent lesions occur in Immunocompromised, organ transplant or AIDS.
Bacterial infections are diagnosed on Clinical grounds, supported by smears, culture, testing for immune responses (Serology) & examining for nucleic acids.
Antibacterial drugs can be effective therapy but, resistance can be a problem (e.g.. MRSA)