Amelogenesis imperfecta is a tooth development disorder in which the teeth are covered with thin, abnormally formed enamel, occasionally in conjunction with other dental, oral and extraoral tissues.. Enamel is composed mostly of mineral, which is formed and regulated by the proteins in it. Amelogenesis imperfecta is due to the malfunction of the proteins in the enamel: ameloblastin, enamelin, tuftelin and amelogenin. Continue reading →