Continued from Part 1
Tobacco and alcohol use are important risk factors for leukoplakia and oral cancer.
Drug-related pemphigoid and other bullous disorders
Drug-induced pemphigoid may be due to drugs acting as haptens or drug-induced immunological dysfunction.
Drugs most commonly implicated
Oral side effects caused by drugs are relatively uncommon but may be important. Some drugs almost invariably cause side effects in the mouth, for example dry mouth from many drugs, and oral ulcerswith some of the cytotoxic agents, while other drugs rarely cause oral complications. Some habits, such as the use of oral snuff (smokeless tobacco), can cause gum recession and leukoplakia (a precancerous white lesion) and possibly predispose to oral cancer whereas oral use of cocaine can cause gum ulceration or peeling of mouth tissues. Drugs that occasionally cause complications in the mouth are discussed below. Continue reading →