Drug induced gingival hyperplasia is one of the common causes of gingival enlargement. Â
There are three types of drugs highly associated with gingival hyperplasia/enlargement :
1) Antiepileptic drug (Phenytoin)
Â 2) Immunosuppressive drug (cyclosporine) and 3) calcium-channel blocking drug (nifedipine).
Phenytoin is usually prescribed for the treatment of seizures where as calcium channel blocking drugs are used to treat heart diseases, angina and hypertension.
Â The incidence of gingival enlargement is lower in patients who are taking cyclosporine compared to patients who are on phenytoin (Approximately 50 % of patients have gingival overgrowth). However, it can be very severe (covers the entire surface of teeth) when gingival enlargement occurs in patients who are taking cyclosporine.Â Continue reading