Tag Archives: down syndrome people

Effect of Systemic Factors on the Periodontium Part 2

Continued from Part 1

Drug reactions

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  • Epanutin/phenytoin/dilantin/DPH – an anticonvulsant drug given to epileptics, some degree of gums enlargement occurs in a large percentage of epileptics taking phenytoin, especially in those under 40 years of age.
  • Cyclosporine – an immunosuppressive drug, it can produce fibrous hyperplasia of the gums. The condition is however less common in patients on cyclosporine, but when it occurs it may be very severe.
  • Nifedipine – a calcium channel blocking drug given to treat cardiac angina, arrhythmias and hypertension, it produces fibrous hyperplasia of the gums. Nifedipine hyperplasia is less firm than the other two, and contains a higher proportion of ground substance. Continue reading