Tag Archives: blisters

Oral pemphigus Part 2

Bullae may present on any oral or oropharyngeal surface, but typically arise in the buccal, palatal and gingival regions. Occasional patients have lesions restricted completely to the gingiva. Skin lesions are similar except that the more heavily keratinized epidermis allows blisters to remain intact much longer. Most patients have circulating autoantibodies which can be detected by indirect immunofluorescence using serum from other affected individuals. Titers are directly proportionate to the severity of the disease. Continue reading